Luiz Augusto Basso Selected Research

Purine-Nucleoside Phosphorylase

1/2013	The transition state analog inhibitor of Purine Nucleoside Phosphorylase (PNP) Immucillin-H arrests bone loss in rat periodontal disease models.
1/2005	Crystal structure of human PNP complexed with hypoxanthine and sulfate ion.
1/2004	Structures of human purine nucleoside phosphorylase complexed with inosine and ddI.

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Luiz Augusto Basso Research Topics

Disease

25	Tuberculosis (Tuberculoses) 01/2021 - 07/2002
5	Infections 11/2017 - 08/2012
4	Neoplasms (Cancer) 07/2021 - 10/2003
2	Purine Nucleoside Phosphorylase Deficiency 01/2005 - 01/2004
1	Virus Diseases (Viral Diseases) 04/2024
1	hypoglycemic encephalopathy 04/2024
1	Severe Acute Respiratory Syndrome 04/2023
1	Colorectal Neoplasms (Colorectal Cancer) 07/2021
1	Fibrosis (Cirrhosis) 01/2021
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021
1	Inflammation (Inflammations) 01/2021
1	Lung Injury 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 12/2020
1	Glioblastoma (Glioblastoma Multiforme) 01/2019
1	Hypoxia (Hypoxemia) 01/2019
1	Alopecia (Baldness) 11/2017
1	Diarrhea 11/2017
1	Cardiotoxicity 03/2016
1	Periodontal Diseases (Periodontal Disease) 01/2013
1	Coinfection 01/2013
1	Malaria 01/2011
1	Toxoplasmosis 01/2009

Drug/Important Bio-Agent (IBA)

6	EnzymesIBA 01/2019 - 01/2004
5	Isoniazid (Ftivazide)FDA LinkGeneric 01/2019 - 11/2014
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 07/2002
3	Thymidine PhosphorylaseIBA 07/2021 - 03/2014
3	shikimate kinaseIBA 01/2013 - 07/2002
3	Adenosine Diphosphate (ADP)IBA 01/2013 - 12/2004
3	Purine-Nucleoside PhosphorylaseIBA 01/2013 - 01/2004
3	shikimateIBA 01/2013 - 12/2004
3	purineIBA 01/2009 - 01/2004
2	InterferonsIBA 04/2024 - 03/2017
2	CPBMF65IBA 01/2021 - 12/2020
2	IronIBA 01/2018 - 11/2014
2	pentacyano(isoniazid)ferrate(II)IBA 11/2017 - 08/2012
2	Antitubercular AgentsIBA 11/2017 - 01/2013
2	Rifampin (Rifampicin)FDA LinkGeneric 01/2017 - 03/2016
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2015 - 01/2011
2	forodesineIBA 01/2013 - 10/2003
1	CytokinesIBA 04/2024
1	Antiviral Agents (Antivirals)IBA 04/2024
1	Metformin (Glucophage)FDA LinkGeneric 04/2024
1	Antigen-Antibody Complex (Immune Complex)IBA 04/2023
1	Fluorouracil (Carac)FDA LinkGeneric 07/2021
1	Angiogenesis InhibitorsIBA 07/2021
1	Uridine PhosphorylaseIBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2021
1	CollagenIBA 01/2021
1	indium-bleomycinIBA 01/2021
1	UridineIBA 01/2021
1	tafenoquineIBA 01/2021
1	PeptidomimeticsIBA 01/2019
1	2-hydroxypyridineIBA 01/2019
1	DNA GyraseIBA 03/2018
1	ProdrugsIBA 01/2018
1	NucleosidesIBA 03/2017
1	Mefloquine (Lariam)FDA LinkGeneric 08/2016
1	oxazolidineIBA 08/2016
1	guanosine 5'-monophosphorothioateIBA 12/2015
1	Nucleic AcidsIBA 07/2014
1	shikimic acid-3-phosphateIBA 01/2013
1	Adenosine Triphosphate (ATP)IBA 01/2013
1	Hydroxyl RadicalIBA 01/2013
1	pentacyano(2- methyl- 5- (pyridin- 4- yl)- 1,3,4- oxadiazole)ferrate(II)IBA 08/2012
1	Proteins (Proteins, Gene)FDA Link 08/2009
1	SolutionsIBA 09/2008
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 09/2008
1	Type C PhospholipasesIBA 07/2007
1	Intergenic DNA (Junk DNA)IBA 07/2007
1	polyethylene glycol 400IBA 04/2006
1	Prephenate DehydrataseIBA 04/2006
1	DeoxyguanosineIBA 10/2003

Therapy/Procedure

4	Therapeutics 01/2018 - 09/2007
1	Ligation 01/2013
1	Drug Therapy (Chemotherapy) 01/2013